Galectin 3 antibody (AA 151-251) (PE)

Catalog No. ABIN2663838

This Mouse Monoclonal antibody specifically detects Galectin 3 in IHC, FACS, IP and BR. It exhibits reactivity toward Human and Mouse.

Quick Overview for Galectin 3 antibody (AA 151-251) (PE) (ABIN2663838)

Target: Galectin 3 (LGALS3)

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Galectin 3 antibody is conjugated to PE

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR)

Clone: Gal397

Product Details anti-Galectin 3 Antibody (PE)

Binding Specificity: AA 151-251

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for Galectin 3

Target: Galectin 3 (LGALS3)

Alternative Name: Mac-2

Target Type: Chemical

Background: Galectin-3 (galactose-specific lectin 3) is a 30-32 kD glycoprotein, also know as Mac-2, Gal-3, RL-29, galactose-specific lectin 3, CBP-35, L-34, and εBP. It is a member of animal β-galactoside-binding protein family that is expressed in cell nucleus, cytoplasm, plasma membrane, or extracellular matrix by variety of tumor cells, monocytes/macrophages, epithelial cells, Kupffer cells, and dendritic cells. Galectin-3 contains carbohydrate recognition domains and binds to β-galactoside residues bearing glycoproteins, such as as IgE, IgA, galactose, casein kinase I, laminin, mucin, LAMPs, and CD66. Galectin-3 is an adhesion molecule and plays an important role in regulation of cell proliferation, differentiation and tumor cell metastasis. Galectin-3 structurely possesses NWGR motif that is conserved in BH-1 domain of BCL-2 family and functions as an anti-apoptotic molecule.

Pathways: RTK Signaling